| Grayson O'Bara | WR | North Texas Mean Green |
|---|
| Hugh O'Brien | WR | Wake Forest Demon Deacons |
|---|
| Joey O'Brien | S | Notre Dame Fighting Irish |
|---|
| Liam O'Brien | QB | Cincinnati Bearcats |
|---|
| Aidan O'Callaghan | TE | Memphis Tigers |
|---|
| Colin O'Carroll | OL | Tulane Green Wave |
|---|
| Ryan O'Connell | LB | USC Trojans |
|---|
| Ethan O'Connor | DB | Miami Hurricanes |
|---|
| Kevin O'Connor | DE | Duke Blue Devils |
|---|
| Michael O'Connor | LS | Rutgers Scarlet Knights |
|---|
| Sean O'Haire | PK | Maryland Terrapins |
|---|
| Tomas O'Halloran | P | East Carolina Pirates |
|---|
| Thomas O'Hara | P | Kentucky Wildcats |
|---|
| Luke O'Hare | LS | Maryland Terrapins |
|---|
| Tomas O'Meara | RB | Michigan Wolverines |
|---|
| Carmelo O'Neal | DB | Alabama Crimson Tide |
|---|
| J.J. O'Neal | S | Missouri State Bears |
|---|
| Danny O'Neil | QB | Wisconsin Badgers |
|---|
| Aidan O'Neill | PK | Kansas State Wildcats |
|---|
| Grady O'Neill | WR | Sam Houston Bearkats |
|---|
| Miles O'Neill | QB | North Carolina Tar Heels |
|---|
| Caden O'Rourke | DL | Northwestern Wildcats |
|---|
| Jayden O'Rourke | TE | Nevada Wolf Pack |
|---|
| Walker O'Steen | LB | Jacksonville State Gamecocks |
|---|
| Garrett Oakley | TE | Kansas State Wildcats |
|---|
| Iman Oates | DT | Oklahoma State Cowboys |
|---|
| John-Patrick Oates | LB | Virginia Tech Hokies |
|---|
| Jehiem Oatis | DT | Ole Miss Rebels |
|---|
| Kevin Oatis | DT | Kansas Jayhawks |
|---|
| Yousef Obeid | PK | Missouri State Bears |
|---|
| Chiddi Obiazor | DL | Indiana Hoosiers |
|---|
| Ify Obidegwu | DB | Oregon Ducks |
|---|
| Kelvin Obot | OL | Utah Utes |
|---|
| Matthew Occhipinti | LB | UCF Knights |
|---|
| Gael Ochoa | QB | Rice Owls |
|---|
| Jordan Ochoa | DL | Nebraska Cornhuskers |
|---|
| Jacob Oden | S | Michigan Wolverines |
|---|
| Ezra Odinjor | DE | Toledo Rockets |
|---|
| Jabari Odoemenem | LB | Oregon State Beavers |
|---|
| AJ Odom | LB | Bowling Green Falcons |
|---|
| Amari Odom | QB | Syracuse Orange |
|---|
| Caleb Odom | TE | Ole Miss Rebels |
|---|
| Jojo Odom | DL | Louisiana Tech Bulldogs |
|---|
| Kenny Odom | WR | South Florida Bulls |
|---|
| Marlin Odom | CB | Troy Trojans |
|---|
| Trajen Odom | DL | Arkansas Razorbacks |
|---|
| Na'eem Offord | DB | Oregon Ducks |
|---|
| Cheta Ofili | LB | TCU Horned Frogs |
|---|
| Joshua Ofor | LB | Arkansas State Red Wolves |
|---|
| Jesse Ofurie | DB | Rutgers Scarlet Knights |
|---|
| Nissi Ogbebor | DL | Syracuse Orange |
|---|
| Nnamdi Ogboko | DL | Georgia Bulldogs |
|---|
| Ahran Ogbor | S | Rice Owls |
|---|
| Daniel Ogordi | DB | Army Black Knights |
|---|
| Matt Ogunniyi | TE | Massachusetts Minutemen |
|---|
| Emmanuel Oguns | DL | Louisiana Tech Bulldogs |
|---|
| Jadyn Oh | PK | Oregon State Beavers |
|---|
| Henry Ohlinger | LB | Indiana Hoosiers |
|---|
| Theo Melin Ohrstrom | TE | SMU Mustangs |
|---|
| Che Ojarikre | CB | Duke Blue Devils |
|---|
| Caleb Ojeda | PK | Oregon State Beavers |
|---|
| Ike Okafor | DT | Washington State Cougars |
|---|
| Odera Okaka | LB | California Golden Bears |
|---|
| David Oke | DL | Arkansas Razorbacks |
|---|
| Timi Oke | DB | Northwestern Wildcats |
|---|
| Chukwunedu Okeke | DL | James Madison Dukes |
|---|
| Obinna Okeke | DE | New Mexico State Aggies |
|---|
| Anthony Okes | DE | North Dakota State Bison |
|---|
| Daniel Okonkwo | S | Georgia Bulldogs |
|---|
| George Okorie | DE | Ball State Cardinals |
|---|
| Justin Okoronkwo | LB | South Carolina Gamecocks |
|---|
| Danny Okoye | DL | Oklahoma Sooners |
|---|
| Emmanuel Okoye | LB | California Golden Bears |
|---|
| Kosi Okpala | LB | Texas Longhorns |
|---|
| Eduwa Okundaye | DE | Washington State Cougars |
|---|
| Samuel Okunlola | DL | Virginia Tech Hokies |
|---|
| Michael-Anthony Okwura | DL | California Golden Bears |
|---|
| Caleb Olabode | LB | Missouri State Bears |
|---|
| Israel Oladipupo | DL | Boston College Eagles |
|---|
| Emmanuel Olagbaju | DL | Iowa Hawkeyes |
|---|
| David Olano | PK | Texas A&M Aggies |
|---|
| Tobi Olawole | WR | Army Black Knights |
|---|
| Jayden Olden | LB | East Carolina Pirates |
|---|
| Andrew Olesh | TE | Oregon Ducks |
|---|
| Jamal Olford | CB | James Madison Dukes |
|---|
| Caleb Oliver | EDGE | Buffalo Bulls |
|---|
| Davontey Oliver | DB | Eastern Michigan Eagles |
|---|
| Jason Oliver | CB | San Diego State Aztecs |
|---|
| John Wayne Oliver | OL | Ole Miss Rebels |
|---|
| Jed Olotu-Judah | LB | Old Dominion Monarchs |
|---|
| Eric Olsen | TE | Oregon State Beavers |
|---|
| Jack Olsen | PK | Miami Hurricanes |
|---|
| Ty Olsen | WR | Utah State Aggies |
|---|
| Quinn Olson | S | Arizona Wildcats |
|---|
| Donovan Olugbode | WR | Missouri Tigers |
|---|
| Joseph Oluwayemi | DL | Eastern Michigan Eagles |
|---|
| Sean Olvera-Harle | PK | Hawai'i Rainbow Warriors |
|---|
| Jaimion Olverson | DE | Bowling Green Falcons |
|---|
| Troy Omeire | WR | New Mexico Lobos |
|---|
| Paul Omodia | DB | Colorado Buffaloes |
|---|
| David Omopariola | LB | Syracuse Orange |
|---|
| Derek Omoregie | DE | UL Monroe Warhawks |
|---|
| Sammy Omosigho | LB | UCLA Bruins |
|---|
| Fawzy Omotoso | DE | Northern Illinois Huskies |
|---|
| Irabonoise Oniha | CB | Navy Midshipmen |
|---|
| Jordan Onovughe | WR | Stanford Cardinal |
|---|
| Kainoa Ontai | DB | Hawai'i Rainbow Warriors |
|---|
| Bo Onu | S | Baylor Bears |
|---|
| David Onuoha | DL | North Texas Mean Green |
|---|
| Sampson Onuoha | DE | Duke Blue Devils |
|---|
| Jayden Onuonga | PK | North Dakota State Bison |
|---|
| Obinna Onwuka | DE | Coastal Carolina Chanticleers |
|---|
| Jason Onye | DL | Notre Dame Fighting Irish |
|---|
| Adrian Onyiego | LB | Oregon State Beavers |
|---|
| Joseph Opara | CB | Sam Houston Bearkats |
|---|
| Jayden Oquendo | DL | Air Force Falcons |
|---|
| Curly Ordonez | LB | Temple Owls |
|---|
| Odera Orizu | DE | UConn Huskies |
|---|
| Alex Orji | QB | UNLV Rebels |
|---|
| Smith Orogbo | EDGE | Texas Longhorns |
|---|
| Malik Orsan | PK | South Carolina Gamecocks |
|---|
| Chase Ortiz | LS | Marshall Thundering Herd |
|---|
| Zach Ortwerth | TE | Iowa Hawkeyes |
|---|
| Lucas Osada | PK | Illinois Fighting Illini |
|---|
| LaDavion Osborn | CB | Toledo Rockets |
|---|
| Hunter Osborne | DL | Arkansas Razorbacks |
|---|
| Javian Osborne | RB | Notre Dame Fighting Irish |
|---|
| Kalieb Osborne | QB | UConn Huskies |
|---|
| Michael Osei-Bonsu | TE | Missouri State Bears |
|---|
| Nick Osho | RB | North Texas Mean Green |
|---|
| Eze Osondu | LB | UTSA Roadrunners |
|---|
| Cade Osterman | WR | North Dakota State Bison |
|---|
| Addison Ostrenga | TE | Iowa Hawkeyes |
|---|
| Ben Osueke | CB | Kansas State Wildcats |
|---|
| Tobi Osunsanmi | DL | Indiana Hoosiers |
|---|
| Jamih Otis | LB | Hawai'i Rainbow Warriors |
|---|
| Caleb Otlewski | LB | Colorado State Rams |
|---|
| Jaxon Ott | LB | Purdue Boilermakers |
|---|
| Greg Otten | LB | South Florida Bulls |
|---|
| Joe Otting | OL | Notre Dame Fighting Irish |
|---|
| André Otto | OL | Florida State Seminoles |
|---|
| Nico Ottomanelli | PK | Sam Houston Bearkats |
|---|
| Chidera Otutu | DL | Cincinnati Bearcats |
|---|
| Issa Ouattara | DL | Vanderbilt Commodores |
|---|
| Braylon Outlaw | LB | Georgia Tech Yellow Jackets |
|---|
| Matthew Outten | WR | Syracuse Orange |
|---|
| Dominic Overby | WR | Iowa State Cyclones |
|---|
| Patrick Overmyer | TE | Houston Cougars |
|---|
| De'yhare Overstreet-Glover | WR | San Diego State Aztecs |
|---|
| Taijh Overton | S | UL Monroe Warhawks |
|---|
| Bisi Owens | WR | Purdue Boilermakers |
|---|
| Chancellor Owens | DL | Texas State Bobcats |
|---|
| Coby Owens | LB | Georgia State Panthers |
|---|
| Daniel Owens | DL | Maryland Terrapins |
|---|
| Eli Owens | TE | Michigan Wolverines |
|---|
| Jamar Owens | DB | Indiana Hoosiers |
|---|
| John Owens | LS | Boston College Eagles |
|---|
| Jordan Owens | LB | Buffalo Bulls |
|---|
| Trey Owens | QB | Arkansas State Red Wolves |
|---|
| Walter Owens | S | New Mexico State Aggies |
|---|
| Martin Owusu | DL | Fresno State Bulldogs |
|---|
| Nathaniel Owusu-Boateng | LB | Michigan Wolverines |
|---|
| Marshon Oxley | LB | South Florida Bulls |
|---|
| Ehimen Oyamendan | DB | Air Force Falcons |
|---|
| Emmanuel Oyebadejo | DL | Florida Gators |
|---|
| Paul Oyewale | LB | TCU Horned Frogs |
|---|
| Jack Oyola | DB | Northwestern Wildcats |
|---|
| Eli Ozick | PK | Iowa Hawkeyes |
|---|
| Kenny Ozowalu | DL | Oklahoma Sooners |
|---|
| Ikenna Ozurumba | DE | Navy Midshipmen |
|---|